Pelvic lymph node metastasis carries the highest impact on decreased survival among surgical-pathological risk factors for early-stage cervical cancer. While concurrent administration of chemotherapy during postoperative radiotherapy is the current standard treatment for surgically-treated high-risk early-stage cervical cancer, its effectiveness specific to node-positive disease has not been completely studied.
Uterine fibroids may decrease quality of life in a significant proportion of affected women. Myomectomy offers a uterine-sparing treatment option for patients with uterine fibroids that can be performed abdominally, laparoscopically (with or without robotic assistance), and by hysteroscopy. Quality of life using validated measures for different myomectomy routes, especially hysteroscopic myomectomy, is limited.
Myomectomy is associated with a significant risk of hemorrhage. Tranexamic acid is a synthetic lysine derivative with antifibrinolytic activity used in other surgical disciplines to reduce blood loss during surgery. However, its utility in gynecologic surgery is not well understood.
The purpose of the present systematic review is to evaluate the available medical treatments for vulvar lichen sclerosus, using an arm based network meta-analysis protocol.
E. Albert Reece, MD, PhD, MBA, has been appointed Associate Editor of Diabetes, Obesity, and Metabolic Disorders during Pregnancy for the American Journal of Obstetrics & Gynecology (AJOG).
The current coronavirus disease 2019 (COVID-19) pneumonia pandemic, caused by the severe acute respiratory syndrome 2 (SARS-CoV-2) virus, is spreading globally at an accelerated rate, with a basic reproduction number (R0) of 2 – 2.5, indicating that 2 – 3 persons will be infected from an index patient. A serious public health emergency, it is particularly deadly in vulnerable populations and communities in which healthcare providers are insufficiently prepared to manage the infection. As of March 16, 2020, there are more than 180,000 confirmed cases of COVID-19 worldwide, with over 7,000 related deaths.
To evaluate the association between opioid prescribing during pregnancy and new persistent opioid use in the year following delivery.
Many cases of placenta accreta spectrum (PAS) are not diagnosed antenatally, despite identified risk factors and improved imaging methods. Identification of plasma protein biomarkers could further improve antenatal diagnosis of PAS.
Uterine fibroids are the most common benign pelvic tumors in women, with complications including heavy menstrual bleeding, pelvic pain, reproductive complications, and bulk-related symptoms. While the majority of uterine fibroids are asymptomatic, those suffering from symptoms can experience substantial burdens on quality of life and daily functioning. Comparative effectiveness reviews into available medical, surgical, and radiological treatments have found that a lack of high-quality data to inform treatment decisions is due, in part, to the use of heterogeneous outcomes and instruments in clinical studies.
Given the accelerating opioid crisis in the United States and evidence that patients use less opioid than prescribed, surgeons may choose to decrease prescribed quantities. The effect this may have on patient satisfaction with pain control after hospital discharge is unknown.